mary2029
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Post by mary2029 on Jul 20, 2020 21:17:09 GMT -5
Ok, do not disagree with what you say here, but why won't the medical community like what you posted previously. There is an incredible wish/desire/need for people to do something. But doing something can be worse than doing nothing. The first tenet of medicine is do no harm, so if we are not sure if something works, not doing it makes sense. These things need to be studied in a scientifically vigorous fashion, so we know what works and what ideas can be discarded. Only way forward. What is frustrating is having them release a statement saying we have a positive result here, without showing the data. Showing the data is necessary, both to corroborate what they are saying, critique it, and to decide the direction things need to go. Ok, well I have just heard that its going to a full scale trial so perhaps its one to watch. Its a safe drug, its used in various forms for other illnesses and there has been a lot of research done on it already.
I just heard on the news that the US is going to have a trial of this for 30K people starting next week. Thanks for sharing!
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pulmonarymd
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Post by pulmonarymd on Jul 20, 2020 21:24:33 GMT -5
Ok, well I have just heard that its going to a full scale trial so perhaps its one to watch. Its a safe drug, its used in various forms for other illnesses and there has been a lot of research done on it already.
I just heard on the news that the US is going to have a trial of this for 30K people starting next week. Thanks for sharing! Different vaccine. The one being studied here is a moderna rna vaccine. The English vaccine is a different company
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mary2029
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Post by mary2029 on Jul 20, 2020 21:53:39 GMT -5
Thanks for the clarification/correction! I thought I heard that the one being tested in the US was from Oxford.
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Spellbound454
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Post by Spellbound454 on Jul 21, 2020 4:50:17 GMT -5
The US has partially funded the Oxford vaccine through the "Operation Warp Speed" and the Gates foundation........ and also ordered doses. The UK has ordered doses from 3 different vaccines as well........ so I think everyone is hedging their bets. Most vaccines will fail...... but there are quite a few in development with different delivery structures.
The Oxford vaccine is undergoing final Phase 111 testing for efficacy in several Countries........... Its safe, its making antibodies..... but it isn't known if it can protect a population, whether it can protect older people or how long the antibodies last........(ideally more than a year and that's a big ask knowing what we already know about corona viruses) You may well be taking part in the Phase 111 trials. Correction: You are taking part in Phase 111 trials.
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pulmonarymd
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Post by pulmonarymd on Jul 21, 2020 6:22:07 GMT -5
The US has partially funded the Oxford vaccine through the "Operation Warp Speed" and the Gates foundation........ and also ordered doses. The UK has ordered doses from 3 different vaccines as well........ so I think everyone is hedging their bets. Most vaccines will fail...... but there are quite a few in development with different delivery structures.
The Oxford vaccine is undergoing final Phase 111 testing for efficacy in several Countries........... Its safe, its making antibodies..... but it isn't known if it can protect a population, whether it can protect older people or how long the antibodies last........(ideally more than a year and that's a big ask knowing what we already know about corona viruses) You may well be taking part in the Phase 111 trials. Correction: You are taking part in Phase 111 trials. Then that’s separate from the trial that was announced, unless it is an rna vaccine
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Spellbound454
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Post by Spellbound454 on Jul 21, 2020 6:37:28 GMT -5
No its on a modified cold virus vector. Its being reported on CNN....https://edition.cnn.com/2020/07/20/health/oxford-covid-19-vaccine-results-cansino-pfizer-study/index.html I think there are trials going on with all the major vaccine contenders. They are heading to areas where they can collect good data.
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pulmonarymd
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Post by pulmonarymd on Jul 21, 2020 7:58:14 GMT -5
No its on a modified cold virus vector. Its being reported on CNN....https://edition.cnn.com/2020/07/20/health/oxford-covid-19-vaccine-results-cansino-pfizer-study/index.html I think there are trials going on with all the major vaccine contenders. They are heading to areas where they can collect good data.
OK, so this is a second trial here in the US. I think there is more than one trial going on in the UK as well. Am I correct?
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Spellbound454
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Post by Spellbound454 on Jul 21, 2020 10:04:21 GMT -5
We have an rna vaccine from Imperial London, its not as far along.
They are testing it here for safety in a cohort of 100, though it does seem to produce antibodies (like the other rna vaccines.) If the Oxford vaccine fails in the population..........and it might........ I think we are looking at Moderna............. or another vaccine with a more simple presentation of a dormant Covid agent. Failing that there will be the Imperial vaccine due next year. It may be they all fail....... but we will undoubtedly find better treatments to cope with this thing..... and get it under control.
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Post by The Walk of the Penguin Mich on Jul 21, 2020 12:27:18 GMT -5
Interesting article. I’m glad to see the thought processes start to move away from a humoral IgG serum response. One of the interesting parts of the paper was that when they tested convalescent plasma IgG fro severe, mild and asymptomatic disease, there was a huge overlap. No SD given though, so hard to know if this is relevant. With the info given, it looks like there is not much difference between mild and severe disease, which kind of brings into question of usefulness of IgG. www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31604-4/fulltext
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Happy prose
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Post by Happy prose on Jul 21, 2020 13:16:24 GMT -5
NJ is for sure looking better, BUT...one lab, Quest (huge) is having a problem, and their numbers are not reported. NJ is all happy that the transmission rate is .9, but isn't that number sketchy, being we are missing huge lab results? I feel like I'm missing something.
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weltschmerz
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Post by weltschmerz on Jul 21, 2020 13:32:22 GMT -5
Canada is also working on vaccines. Unlike traditional vaccine development, Medicago does not use animal products or live viruses to create its products. The company says it uses “virus-like particles (VLPs) that mimic the shape and dimensions of a virus, which allows the body to recognize them and create an immune response in a non-infectious way.” Landry says its COVID-19 vaccine candidate stimulated a “very high neutralizing antibody response” in mice, along with activating the body’s T-cells, a major component of the immune system. Medicago is evaluating three dosage levels of the vaccine, both alone and in conjunction with two already-approved adjuvants. www.ctvnews.ca/health/coronavirus/the-hunt-for-a-vaccine-canadian-company-begins-human-testing-of-covid-19-candidate-1.5022960
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NastyWoman
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Post by NastyWoman on Jul 21, 2020 16:30:26 GMT -5
The US has partially funded the Oxford vaccine through the "Operation Warp Speed" and the Gates foundation........ and also ordered doses. Ooohhh. That is bad. You'll all get the "Gates tracking chip" implanted
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Spellbound454
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Post by Spellbound454 on Jul 21, 2020 16:46:08 GMT -5
Interesting article. I’m glad to see the thought processes start to move away from a humoral IgG serum response. One of the interesting parts of the paper was that when they tested convalescent plasma IgG fro severe, mild and asymptomatic disease, there was a huge overlap. No SD given though, so hard to know if this is relevant. With the info given, it looks like there is not much difference between mild and severe disease, which kind of brings into question of usefulness of IgG. www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31604-4/fulltextYes this is the Oxford vaccine. It all hangs on whether the antibodies will stop the virus and will last long enough
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thyme4change
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Post by thyme4change on Jul 21, 2020 17:02:08 GMT -5
The US has partially funded the Oxford vaccine through the "Operation Warp Speed" and the Gates foundation........ and also ordered doses. Ooohhh. That is bad. You'll all get the "Gates tracking chip" implanted I already have the Zuckerberg tracking chip. I also have the Google chip - that is the super bad one. It knows EVERYTHING. And that was before Alexa moved in. Now Google knows way more. Google knows the temperature inside my house. It knows what we had for dinner. It knows absolutely everything. Not sure the Gates chip will do that the Google chip doesn't already do.
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steff
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Post by steff on Jul 22, 2020 13:50:11 GMT -5
We got hubby's test results back today. He's NEGATIVE!!! No plague here. He's been released from lock down upstairs.
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anciana
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Post by anciana on Jul 22, 2020 14:20:16 GMT -5
We got hubby's test results back today. He's NEGATIVE!!! No plague here. He's been released from lock down upstairs. What a relief this must be for you and your family! So happy for you all!
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andi9899
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Post by andi9899 on Jul 22, 2020 15:17:14 GMT -5
I had a heated conversation with my DT supporter dad last night. He was talking about how the system let my nephew down and now he's going to miss his senior year of HS and he wants to go. I informed him it was in fact the orange man that he helped put in the WH house that let him down. He said it was all the governors not locking states down that were to blame. I told him that governors aren't in charge of the US, the president is and instead of handling it he insisted it was a hoax to make him look bad. I pointed out the rate at which people are dying in other countries compared to here. Then he said "People die all the time. They get shot, they get in car accidents, etc." I finally had enough and told him, "Yeah, and now 140,000+ Americans are dead. Cause of death, incompetence." I also informed my father that he's full of $hit. I just can't. That was just the cliff notes. There was more. He also stated that he's voting for him again this election. You can't make this crap up. Well well well. Guess who can't smell or taste anything now. My 17 yo nephew. I told my dad this would happen. They refuse to social distance or and have only recently started wearing masks because the city has now mandated it. According to my dad he's young and will be just fine if he has it. My dad better hope to God nephew tests negative. If not I'm kicking my dad's ass. Nephew works at a restaurant and they still want him to come in since his test hasn't come back yet so he's not officially positive. WTF?!
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andi9899
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Post by andi9899 on Jul 22, 2020 15:18:01 GMT -5
We got hubby's test results back today. He's NEGATIVE!!! No plague here. He's been released from lock down upstairs. Yay!
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haapai
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Post by haapai on Jul 22, 2020 15:50:50 GMT -5
I had a heated conversation with my DT supporter dad last night. He was talking about how the system let my nephew down and now he's going to miss his senior year of HS and he wants to go. I informed him it was in fact the orange man that he helped put in the WH house that let him down. He said it was all the governors not locking states down that were to blame. I told him that governors aren't in charge of the US, the president is and instead of handling it he insisted it was a hoax to make him look bad. I pointed out the rate at which people are dying in other countries compared to here. Then he said "People die all the time. They get shot, they get in car accidents, etc." I finally had enough and told him, "Yeah, and now 140,000+ Americans are dead. Cause of death, incompetence." I also informed my father that he's full of $hit. I just can't. That was just the cliff notes. There was more. He also stated that he's voting for him again this election. You can't make this crap up. Well well well. Guess who can't smell or taste anything now. My 17 yo nephew. I told my dad this would happen. They refuse to social distance or and have only recently started wearing masks because the city has now mandated it. According to my dad he's young and will be just fine if he has it. My dad better hope to God nephew tests negative. If not I'm kicking my dad's ass. Nephew works at a restaurant and they still want him to come in since his test hasn't come back yet so he's not officially positive. WTF?! WTF indeed. My own company changed the rules back in April to make returning to work while awaiting a test result a big, big no-no. They may have only done this because it was already a misdemeanor. What is this restaurant thinking?
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andi9899
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Post by andi9899 on Jul 22, 2020 15:55:53 GMT -5
Well well well. Guess who can't smell or taste anything now. My 17 yo nephew. I told my dad this would happen. They refuse to social distance or and have only recently started wearing masks because the city has now mandated it. According to my dad he's young and will be just fine if he has it. My dad better hope to God nephew tests negative. If not I'm kicking my dad's ass. Nephew works at a restaurant and they still want him to come in since his test hasn't come back yet so he's not officially positive. WTF?! WTF indeed. My own company changed the rules back in April to make returning to work while awaiting a test result a big, big no-no. They may have only done this because it was already a misdemeanor. What is this restaurant thinking?
I don't know. It's a very busy and big franchise. He's their go to because he goes in whenever they are shorthanded without question. He's trying to stack up a bunch of cash so he can move out when he turns 18. I know I won't be going there any time soon if that's how they operate.
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thyme4change
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Post by thyme4change on Jul 22, 2020 15:57:22 GMT -5
WTF indeed. My own company changed the rules back in April to make returning to work while awaiting a test result a big, big no-no. They may have only done this because it was already a misdemeanor. What is this restaurant thinking?
I don't know. It's a very busy and big franchise. He's their go to because he goes in whenever they are shorthanded without question. He's trying to stack up a bunch of cash so he can move out when he turns 18. I know I won't be going there any time soon if that's how they operate. Another good reason to stay out of restaurants in general. Who knows how each one, each location, each manager is handling things.
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NomoreDramaQ1015
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Post by NomoreDramaQ1015 on Jul 22, 2020 16:15:21 GMT -5
WTF indeed. My own company changed the rules back in April to make returning to work while awaiting a test result a big, big no-no. They may have only done this because it was already a misdemeanor. What is this restaurant thinking?
I don't know. It's a very busy and big franchise. He's their go to because he goes in whenever they are shorthanded without question. He's trying to stack up a bunch of cash so he can move out when he turns 18. I know I won't be going there any time soon if that's how they operate. I'm surprised. Here if they found out my dad was letting someone work who is a potential positive he could be shut down. His mom kept dwaddling so finally Dad had to tell her either get his ass tested or he's done because he is NOT coming back without a negative test result. We wanted doctor's proof he went too. Course how many servers are going to be willing to report their bosses right now? It's not like there is an abundance of jobs to go around.
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pulmonarymd
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Post by pulmonarymd on Jul 22, 2020 16:35:51 GMT -5
And again, this is why we will not get the pandemic under control anytime soon. Compassionate and intelligent sick policies are needed right now. And a restaurant! Glad I do not live in Andi's state
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billisonboard
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Post by billisonboard on Jul 22, 2020 16:57:02 GMT -5
And then the other side. The owner of a local franchise burger drive-in closed their small inside order/sitting area because of the abuse customers were giving her staff attempting to enforce our state mandated mask policy. She said she had a diuretic people quit because it was so bad.
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andi9899
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Post by andi9899 on Jul 22, 2020 17:13:09 GMT -5
I don't know why they think it's a good idea to have him still go in. I also don't know if he's planning to still go in. I really hope that my sister won't allow him to, but they're not exercising the best judgment right now.
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Spellbound454
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Post by Spellbound454 on Jul 22, 2020 18:33:04 GMT -5
No he has to stay at home and isolate..... and order a test straight away. and stay away from other relatives until he has the all clear. Nobody has a right to be served when its a private business. If people don't want to abide by the rules set out by the establishment........don't go there. Simples
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Spellbound454
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Post by Spellbound454 on Jul 22, 2020 18:41:55 GMT -5
I don't know what its like where you are........... but some businesses he have lost a load of custom because the has been a rumour that they are not taking the precautions seriously enough. People want to feel safe when they are shopping/eating. Oh, Its just been on the news that for the 54 Counties in Africa....they only have 41 ventilators....... Good Grief They are asking for a fair share of vaccines and therapeutics..........and they must have them.
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weltschmerz
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Post by weltschmerz on Jul 22, 2020 18:54:57 GMT -5
And then the other side. The owner of a local franchise burger drive-in closed their small inside order/sitting area because of the abuse customers were giving her staff attempting to enforce our state mandated mask policy. She said she had a diuretic people quit because it was so bad. What?? People on diuretics quit?
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billisonboard
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Post by billisonboard on Jul 22, 2020 19:09:02 GMT -5
And then the other side. The owner of a local franchise burger drive-in closed their small inside order/sitting area because of the abuse customers were giving her staff attempting to enforce our state mandated mask policy. She said she had a diuretic people quit because it was so bad. What?? People on diuretics quit? whoops.
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weltschmerz
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Post by weltschmerz on Jul 22, 2020 23:27:45 GMT -5
What?? People on diuretics quit? whoops. Yes, but what did you mean?
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