weltschmerz
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Post by weltschmerz on Sept 18, 2020 15:06:43 GMT -5
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happyhoix
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Post by happyhoix on Sept 18, 2020 15:34:58 GMT -5
Transportation won’t be the problem- there is a network of distribution sites for the storage and distribution of drugs at all temps.
The bottleneck will be the production of such a large quantity of vaccine. Production suites for vaccines are expensive and elaborate- not easy to rapidly create them.
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NomoreDramaQ1015
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Post by NomoreDramaQ1015 on Sept 18, 2020 15:37:42 GMT -5
Well it likely will be.. .for him, his family and all the rich white men in Congress. For us peons it's going to take awhile.
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justme
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Post by justme on Sept 18, 2020 15:40:31 GMT -5
So are these companies going to be mass producing the vaccine before it's even officially approved? That seems....risky, but I'm not in that industry so maybe not.
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Ryan
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Post by Ryan on Sept 18, 2020 15:56:41 GMT -5
I was pretty sure the vaccines are already being produced, partially due to funding from the US gov't. I don't know how likely it is that it will be done within 2 days, but these companies are in Phase 3 trials and are vaccinating 30K people. So like NoMoreDrama said, some people probably will get vaccinated pretty quick.
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Ryan
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Post by Ryan on Sept 18, 2020 16:05:51 GMT -5
Now that things are settling down with regard to COVID (at least where I live), it's interesting to see people's attitude towards the vaccine. In April, everyone would've jumped at the opportunity for the vaccine, probably in July as well. Now? I asked 4 people that I work with that have been pretty cautious and they said that they would not get it when it becomes available.
I am guessing that people think that if a portion of the people get it, combined with the people that had COVID, then they'd be much safer.
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billisonboard
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Post by billisonboard on Sept 18, 2020 16:11:37 GMT -5
There are a lot of highly competent professionals working on this issue.
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billisonboard
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Post by billisonboard on Sept 18, 2020 16:18:17 GMT -5
Now that things are settling down with regard to COVID (at least where I live), it's interesting to see people's attitude towards the vaccine. In April, everyone would've jumped at the opportunity for the vaccine, probably in July as well. Now? I asked 4 people that I work with that have been pretty cautious and they said that they would not get it when it becomes available. I am guessing that people think that if a portion of the people get it, combined with the people that had COVID, then they'd be much safer. You asked them if they would get the vaccine and then guessed about their reasoning for their answer?
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justme
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Post by justme on Sept 18, 2020 16:23:38 GMT -5
Well, yea, they obviously had to produce enough vaccines for the trial and will undoubtedly have produced more than they need so there will be some level of supply sitting around once it's produced. But I wouldn't think, at least normally, that they would have an excessive quantity of a vaccine sitting around before it's approved. I suppose it depends on how likely things are that get to phase 3 are to ultimately be approved.
But like I said my expereince isn't in this industry. But I know in orders my company has done the producer wouldn't make items to our specifications until it was fully approved. Would have though a vaccine - which couldn't be repurposed into something else - would have been similar. What good is 100k vaccines if it's not approved?
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Post by The Walk of the Penguin Mich on Sept 18, 2020 16:32:20 GMT -5
This is the least of it. Storing at -80C is not an issue, we store things like this all the time. My last job, we had 6 -80 freezers. We transport things this cold frequently as well. Any lab will have a freezer this cold. You can also store in liquid nitrogen. There are specific tanks that allow you to store thousands of vials like this. It really isn’t a problem.
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Post by The Walk of the Penguin Mich on Sept 18, 2020 16:35:22 GMT -5
Now that things are settling down with regard to COVID (at least where I live), it's interesting to see people's attitude towards the vaccine. In April, everyone would've jumped at the opportunity for the vaccine, probably in July as well. Now? I asked 4 people that I work with that have been pretty cautious and they said that they would not get it when it becomes available. I am guessing that people think that if a portion of the people get it, combined with the people that had COVID, then they'd be much safer. My best guess is that the political pressure provided to pharmaceutical companies has increased to the point where many feel like a vaccine will be released only due to political reasons.....not due to efficacy. TBH, I’m not interested in getting any sort of vaccine that there is no efficacy and it might have harmful side effects.
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weltschmerz
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Post by weltschmerz on Sept 18, 2020 16:38:08 GMT -5
This is the least of it. Storing at -80C is not an issue, we store things like this all the time. My last job, we had 6 -80 freezers. We transport things this cold frequently as well. Any lab will have a freezer this cold. You can also store in liquid nitrogen. There are specific tanks that allow you to store thousands of vials like this. It really isn’t a problem. Do many doctors offices, pharmacies and clinics have vats of liquid nitrogen? How about cryogenic freezers?
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Post by The Walk of the Penguin Mich on Sept 18, 2020 16:39:09 GMT -5
I was pretty sure the vaccines are already being produced, partially due to funding from the US gov't. I don't know how likely it is that it will be done within 2 days, but these companies are in Phase 3 trials and are vaccinating 30K people. So like NoMoreDrama said, some people probably will get vaccinated pretty quick. If you consider that the last dosing of vaccine in the phase 3 trial is the end of October, there is absolutely no way they are going to get any efficacy data before the end of the year. They can determine if it elicits an antibody, but the only way to know if the antibody is effective is to challenge. It is not possible to challenge with a live virus due to ethical reasons.....so it becomes a numbers game, looking at the difference between cases in experimental and control.
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Post by The Walk of the Penguin Mich on Sept 18, 2020 16:42:46 GMT -5
This is the least of it. Storing at -80C is not an issue, we store things like this all the time. My last job, we had 6 -80 freezers. We transport things this cold frequently as well. Any lab will have a freezer this cold. You can also store in liquid nitrogen. There are specific tanks that allow you to store thousands of vials like this. It really isn’t a problem. Do many doctors offices, pharmacies and clinics have vats of liquid nitrogen? How about cryogenic freezers? In my experience, yes. I have had warts frozen off with liquid nitrogen in my doctor’s office. It’s commonly used in some cooking applications too. Most labs I have worked in got monthly delivery of liquid nitrogen canisters from gas supply companies. Any place associated with a medical center will have easy access to it.
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pulmonarymd
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Post by pulmonarymd on Sept 18, 2020 17:13:51 GMT -5
They just need to set up distribution centers. Will be more efficient than sending it to individual physicians. Then set up drive through vaccinations. Easy enough to plan for. Number of doses will be limiting factor
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NomoreDramaQ1015
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Post by NomoreDramaQ1015 on Sept 18, 2020 17:33:04 GMT -5
Do many doctors offices, pharmacies and clinics have vats of liquid nitrogen? How about cryogenic freezers? In my experience, yes. I have had warts frozen off with liquid nitrogen in my doctor’s office. It’s commonly used in some cooking applications too. Most labs I have worked in got monthly delivery of liquid nitrogen canisters from gas supply companies. Any place associated with a medical center will have easy access to it. I have a scar on my knee where I got myself with liquid nitrogen. Man that hurt! Our tank was tall enough I had to use a step stool. I whacked myself as I lowered the rack to the floor
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Post by The Walk of the Penguin Mich on Sept 18, 2020 18:59:01 GMT -5
In my experience, yes. I have had warts frozen off with liquid nitrogen in my doctor’s office. It’s commonly used in some cooking applications too. Most labs I have worked in got monthly delivery of liquid nitrogen canisters from gas supply companies. Any place associated with a medical center will have easy access to it. I have a scar on my knee where I got myself with liquid nitrogen. Man that hurt! Our tank was tall enough I had to use a step stool. I whacked myself as I lowered the rack to the floor Yep. We had a big tank too.
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justme
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Post by justme on Sept 18, 2020 19:13:10 GMT -5
I was pretty sure the vaccines are already being produced, partially due to funding from the US gov't. I don't know how likely it is that it will be done within 2 days, but these companies are in Phase 3 trials and are vaccinating 30K people. So like NoMoreDrama said, some people probably will get vaccinated pretty quick. If you consider that the last dosing of vaccine in the phase 3 trial is the end of October, there is absolutely no way they are going to get any efficacy data before the end of the year. They can determine if it elicits an antibody, but the only way to know if the antibody is effective is to challenge. It is not possible to challenge with a live virus due to ethical reasons.....so it becomes a numbers game, looking at the difference between cases in experimental and control. I told my friend who likely got the real shot (has antibodies now, but hasn't tested positive for the virus during the trial) and told him now he he needs to go out and lick people and things so I know how well it works. He did not agree.
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Post by The Walk of the Penguin Mich on Sept 18, 2020 19:20:56 GMT -5
If you consider that the last dosing of vaccine in the phase 3 trial is the end of October, there is absolutely no way they are going to get any efficacy data before the end of the year. They can determine if it elicits an antibody, but the only way to know if the antibody is effective is to challenge. It is not possible to challenge with a live virus due to ethical reasons.....so it becomes a numbers game, looking at the difference between cases in experimental and control. I told my friend who likely got the real shot (has antibodies now, but hasn't tested positive for the virus during the trial) and told him now he he needs to go out and lick people and things so I know how well it works. He did not agree. You should have told him to kiss everyone!
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justme
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Post by justme on Sept 18, 2020 19:30:46 GMT -5
I told my friend who likely got the real shot (has antibodies now, but hasn't tested positive for the virus during the trial) and told him now he he needs to go out and lick people and things so I know how well it works. He did not agree. You should have told him to kiss everyone! Darn!
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Post by The Walk of the Penguin Mich on Sept 18, 2020 22:10:36 GMT -5
You should have told him to kiss everyone! Darn! He could have had fun exposing himself!
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Tennesseer
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Post by Tennesseer on Sept 18, 2020 22:17:53 GMT -5
He could have had fun exposing himself! I read today people who wear glasses on a regular basis are less inclined to contract the virus. Less touching of the eyes.
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countrygirl2
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Post by countrygirl2 on Sept 18, 2020 22:19:47 GMT -5
I will wait awhile. I can't imagine getting something trump approved.
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justme
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Post by justme on Sept 18, 2020 23:14:23 GMT -5
He could have had fun exposing himself! Haha maybe, or the convo would turn into a mutual bitch fest of how hard it is to date now when it was hard before.
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dondub
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Post by dondub on Sept 18, 2020 23:36:31 GMT -5
He could have had fun exposing himself! I read today people who wear glasses on a regular basis are less inclined to contract the virus. Less touching of the eyes. I wear contacts and would never leave the house with my glasses on. For months now I’ve been wearing the glasses almost all the time for that exact reason. Now Donnadub and the Dubettes want me to go to Warby Parker and get snazzy. 😎
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Tennesseer
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Post by Tennesseer on Sept 18, 2020 23:56:28 GMT -5
I read today people who wear glasses on a regular basis are less inclined to contract the virus. Less touching of the eyes. I wear contacts and would never leave the house with my glasses on. For months now I’ve been wearing the glasses almost all the time for that exact reason. Now Donnadub and the Dubettes want me to go to Warby Parker and get snazzy. 😎 Had to look to see what a Warby Parker was.
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djAdvocate
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Post by djAdvocate on Sept 19, 2020 1:25:00 GMT -5
Now that things are settling down with regard to COVID (at least where I live), it's interesting to see people's attitude towards the vaccine. In April, everyone would've jumped at the opportunity for the vaccine, probably in July as well. Now? I asked 4 people that I work with that have been pretty cautious and they said that they would not get it when it becomes available. I am guessing that people think that if a portion of the people get it, combined with the people that had COVID, then they'd be much safer. I am guessing that they figure Trump will rush the vaccine through, which will make it unsafe.
there is no other rational reason to avoid it.
herd immunity will kill millions of Americans. it is why Trump opposed it until recently. but he is waving the white flag. he has given up.
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djAdvocate
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Post by djAdvocate on Sept 19, 2020 1:29:04 GMT -5
Now that things are settling down with regard to COVID (at least where I live), it's interesting to see people's attitude towards the vaccine. In April, everyone would've jumped at the opportunity for the vaccine, probably in July as well. Now? I asked 4 people that I work with that have been pretty cautious and they said that they would not get it when it becomes available. I am guessing that people think that if a portion of the people get it, combined with the people that had COVID, then they'd be much safer. You asked them if they would get the vaccine and then guessed about their reasoning for their answer? this reply is pure genius, bills. /\
KUDOS!!!
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happyhoix
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Post by happyhoix on Sept 19, 2020 8:16:27 GMT -5
So are these companies going to be mass producing the vaccine before it's even officially approved? That seems....risky, but I'm not in that industry so maybe not. It’s pretty standard in the industry to start production before final approval if you think it’s a good bet. Especially in this instance where many governments are helping foot the bill and the need is so strong. Plus, since we know production will be a bottle neck, they will want to get a jump on production even if they have to scrap some later.
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countrygirl2
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Post by countrygirl2 on Sept 19, 2020 9:06:33 GMT -5
I think trump will push this through without proper evaluation. He is messing with the CDC and the FDA. How can you trust anything he does. I have so many bad reactions anyway that I need to wait and see how others fare first.
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