Question about CBD oil

[countrygirl2]

I am having pain, the arthrotec and hydrocodone are not really taking care of it and at times I'm adding ibuprophen.  I don't want to take more and more stuff.

Today at Fresh Thyme I asked about something for pain. The person in that area suggested CBD Oil, after reading apparently its made from cannabis. Now I have been an anti marijuana person and still am. But pain makes you start rethinking possibilities.

This stuff says 5mg CBDA/CBD.  Then it says on the side hemp oil 60mg.  What I'm wondering if I take these pills will I test positive for marijuana use.  I want to try it and see if it helps, but I don't want to withdraw from my pain management doctor unless it helps.  They do randomly test you for other drugs, I have had one test already.  Another when I went in the ER, so I  have been tested twice in the last 6 months.  I guess having a reaction to an antibiotic they figured I was lying, I was not an am clean as a whistle.

Then it says helps you sleep, etc but I certainly don't want to trade one drug for another.  What are thoughts about this stuff. Also need to read and see if

it interacts with levothyroxine, Lipitor, or Plavix. 

I'm really debating on whether I should try it or not, I have not at this time.

[chapeau]

As far as I know, medical marijuana does not contain HTC, which is the ingredient in pot that makes you high. Does the oil list active and inactive ingredients?

Try this link: www.pa.gov/guides/pennsylvania-medical-marijuana-program/

Does Indiana have a medical marijuana law? I’m guessing that the place you bought it isn’t selling an illegal product openly.

[Jaguar]

I'm watching this thread, so watch what you post, please.


Jaguar - Administrator

[justme]

My sil talks about copaiba oil. Supposedly similar to the medical part of the weed but not illegal.

www.doterra.com/US/en/p/copaiba-oil

[countrygirl2]

Why are you watching it, its a legitimate question.

I didn't know this, I never heard of the stuff till today.

Store owners will be able to continue selling cannabidiol, or CBD oil, products while Indiana lawmakers work toward clarifying the legality of the substance.

Gov. Eric Holcomb announced Friday an extension of an enforcement moratorium on CBD oil that was set to expire this week.

Attorney General Curtis Hill issued an opinion in November declaring CBD oil illegal in Indiana after much confusion over a law the legislature passed in 2017 intended to allow the product for epilepsy patients.

However, for the first 60 days after that opinion, Gov. Eric Holcomb said that excise police would only issue warnings to stores selling the substance, giving them time to pull the product from store shelves and lawmakers time to pass clarifying legislation.

Holcomb announced in a statement Friday that excise police won't take any action against stores carrying CBD oil while lawmakers are in session. This year's session must end by March 14.

"I said back in November that I was open to extending the education period on CBD oil products to give legislators the time they need to add clarity to Indiana law," Holcomb said. "Lawmakers have indicated they would like more time to consider proposed legislation."

More: Did Indiana legalize cannabis? Yes. Kind of. Maybe.

More: Indiana takes small step toward legalizing medical marijuana as House votes to study issue

Hoosier Politics Newsletter: Get more politics coverage sent straight to your inbox every Thursday

Legislators drafted at least 10 bills this year related to CBD oil in an attempt to fix confusion over the 2017 law that created a CBD oil registry for epileptic patients. Products from nearly 60 stores were seized following the creation of the registry, before the Alcohol and Tobacco Agency announced a moratorium on the seizures.

Two of the CBD bills that already passed out of committees would legalize CBD oil as long as it contains less than .3 percent THC, the substance responsible for the "high" in marijuana. A third bill would take the law a step further and allow farmers to grow industrial hemp, the cannabis plant with low THC.

Holcomb's enforcement moratorium only applies to the state excise police. It does not necessarily provide immunity from local police units.

Call IndyStar reporter Kaitlin Lange at [phone]. Follow her on

[Sharon]

I believe the 9th circuit court recently ruled that CBD was to be considered a class 1/schedule 1 drug.  Even though it does not contain THC that would make you high.  I wouldn't risk it if they are already drug testing you.  If you were to test positive could it affect your guardianship of your DD or MIL.

[Sharon]

Have you ever tried Traumeel?  I think it has been rebranded as T-Relief.   I rub it on my knees and ankles when they really get to hurting and it is the best stuff.

[countrygirl2]

I just don't know.

I just don't know, nothing definite that it will help.  I don't want to try something that will just make the situation worse, sigh.  The stuff I am taking now doesn't leave me feeling good.  I don't like how what they have me on makes me feel.  


Now legal in Indiana, CBD oil open for wide-ranging medical uses

The Times of Northwest Indiana · 6d

On March 21, Indiana Gov. Eric Holcomb signed into law Senate Enrolled Act 52, which legalized cannabidiol oil in Indiana. Both houses of the state Legislature had voted overwhelmingly in favor …

How Indiana's Legalization of CBD Oil Will Impact Workplace Drug Testing

JD Supra · 5d

Senate Enrolled Act 52 was signed into law (Public Law 153), legalizing the sale and use of cannabis-derived CBD oil (with a THC level of 0.3 percent or lower) throughout Indiana. The Act’s passage …

CBD Oil: All the Rage, But Is It Really Safe and Effective?

philly.com · 12h

... oil is legal in 30 states where medicinal and/or recreational marijuana is legal, according to Governing magazine. Seventeen additional states have CBD-specific laws on the books, according to …












Strong Evidence for Treating Epilepsy

Only one purported use for cannabidiol, to treat epilepsy, has significant scientific evidence supporting it.

Last month, a U.S. Food and Drug Administration advisory panel unanimously recommended approval of the CBD medication Epidiolex to treat two rare forms of childhood epilepsy.

"That's really the only area where the evidence has risen to the point where the FDA has said this is acceptable to approve a new drug," said Timothy Welty, chair of the department of clinical sciences at Drake University's College of Pharmacy and Health Sciences, in Des Moines, Iowa.

For the rest of CBD's potential uses, there is simply too little evidence to make a firm conclusion.

For example, some human clinical trials suggest that CBD could be effective in treating symptoms of anxiety, particularly social anxiety, Bonn-Miller said.

This is the potential use for CBD with the most evidence after usefulness in epilepsy, but "there's a decent gap between those two," he said.

"There have been clinical trials in adults, but a lot smaller than the epilepsy studies that have been done in kids," Bonn-Miller said.

CBD's usefulness as an anti-inflammatory medication is the next most promising, but those results come mostly from animal studies, experts said.

Most Other Uses Largely Unproven

The rest of the potential uses -- as an antipsychotic, antidepressant or sleep aid "have all been studied in animals, with only one or two examples of studies in humans," Bonn-Miller said.

And Welty said the studies that have featured humans for these other CBD uses have either been case reports or studies that did not compare results against a control group that did not use the oil.








"There's no control, so it's basically how do you know if we're dealing with the true effect of the drug or just simply a placebo effect because somebody thinks they've been given a drug that will be beneficial?" Welty said.

There also are concerns about both the quality of CBD oil being produced and its potential side effects, the experts added.

Lack of Regulation Also Concerning

Because of the legally murky nature of marijuana, the FDA has not stepped in to regulate products like CBD oil, Bonn-Miller said. States are struggling to put regulations in place, but they don't have the deep pockets of the federal government.

Meanwhile, a 2017 study led by Bonn-Miller found that nearly 7 of 10 CBD products didn't contain the amount of marijuana extract promised on the label.

Nearly 43 percent of the products contained too little CBD, while about 26 percent contained too much, Bonn-Miller said.

"CBD is kind of a tricky drug because it's not very well absorbed orally," Welty explained. "Less than 20 percent of the drug is absorbed orally. If it isn't made in the right way, you may not be getting much drug into your systemic circulation."

Worse, about 1 in 5 CBD products contained the intoxicating pot chemical THC, Bonn-Miller and his colleagues found.

"That's a problem because THC can increase anxiety. It can actually make seizures worse. Those are the sorts of things you need to be careful about," Bonn-Miller said.

"If I were a consumer, purchasing it for myself or my kid, I would want to test it so that I knew what it actually had in it, because I couldn't trust what was on the label," Bonn-Miller concluded.

Potential Interactions With Other Meds

Studies on CBD also have raised concerns about possible interactions with other drugs.

For example, epilepsy studies found that "there were very clearly increases in the blood levels of some other anti-epileptic drugs when people were on CBD," Welty said.

This could mean that people taking anti-epilepsy drugs alongside CBD will need to adjust their dosage downward to avoid side effects, Welty noted.

There also is some indication that CBD might harm the liver. About 10 percent of people taking CBD in studies had increases in liver enzymes, which would indicate possible liver damage, Welty said.

"About 2 to 3 percent of individuals taking CBD actually had to discontinue because their liver enzymes went so high it was of concern to the people running the study," he said.



Welty recommends that people interested in CBD seek out a doctor who has read up on the extract and its potential uses.

"My bottom-line advice is people really need to be under the care of a health care provider who understands CBD. They need to be monitored and managed by that individual, and not just go out and buy CBD thinking it's going to be the answer," Welty said.

More information

The U.S. National Institutes of Health has more about cannabidiol.





SOURCES: Marcel Bonn-Miller, Ph.D., adjunct assistant professor, psychology in psychiatry, University of Pennsylvania School of Medicine, Philadelphia; Timothy Welty, Pharm.D., chair, department of clinical sciences, College of Pharmacy and Health Sciences, Drake University, Des Moines, Iowa

Copyright © 2018 HealthDay. All rights reserved.

More Coverage

Marijuana boosters hail FDA approval of pot-based epilepsy drug. Is it a win for weed?

Apr 20 - 11:02 AM

Published: May 7, 2018 — 3:01 AM EDT | Updated: May 7, 2018 — 9:00 AM EDT

[countrygirl2]

Oh  I never thought about the guardianship issues.  It sounds like Indiana legalized this stuff but that's all I need.  Darn I paid

$25 for the bottle of it. Like I said once I found out what was in it I wondered if I should even buy it.

I just get so tired of hurting all the time, back, feet, mid back, rib cage,  some days its just awful..  But I don't think I will take the

stuff.  I don't want to create issues, I have never been in trouble for anything, squeaky clean old person, want to stay that way.

[Jaguar]

Don't worry about me watching it, you are asking medical questions and that's all fine, I asked already.


I know people who take this cause NOTHING else works for them. I asked my doctors about it and was told that only my family doctor could prescribe this for me. BUT I had tried it already and found for me it just wasn't as good as brainwave entrainment has been for me.

The people I know who take this swear by it, and it's taken for pain and depression. It helps them, it doesn't help me. You need to try it for a week, like I did, so you can make a good decision.


The people who I know that take this are in their early/mid 50's to late 60's.


Good Luck!

[countrygirl2]

I'm going to talk to doc, since I've been taking Lipitor and Plavix I just feel so much worse.  No energy, seem to hurt worse then before.

My arms have black and blue marks up and down them, some big some small, horribly ugly.  I'm making myself do stuff but lots of

the time now I just don't feel right.  I have an appointment Wednesday and going to see if we can reduce the dose of the Plavix or something.  

Was just trying to get off some stuff and hoping something else could help.

[countrygirl2]

But I would never do anything to jeopardize my taking care of DD so its out.

[weltschmerz]

I know several people who use  CBD oil or capsules. One gal at work was so crippled with arthritis, she was off sick for a very long time, and on disability. She tried the capsules on her doctor's advice and now she's back at work and feeling great. HR knows and they're fine with it.
CBD doesn't get you high.
I do the stuff "straight" when I'm feeling poorly and it really helps.

Are you looking for a job, that you're concerned about testing positive?
Will you lose your government security clearance? 

[weltschmerz]

May 7, 2018 22:16:45 GMT -5 countrygirl2 said:

But I would never do anything to jeopardize my taking care of DD so its out.

Wait...CBD oil is out? How would it jeopardize taking care of DD? It doesn't have psychoactive ingredients.
You're far more likely to have major untoward effects from regular pharmaceuticals.
Arthrotec damn near killed me....I even got the Last Rites, because I wasn't expected to survive. 
I would say THAT would kind of jeopardize my being able to look after DS.

[Jaguar]

Pat you need to find out for sure if taking this will affect your guardianship with your DD. You need to ask your doctor about taking Lipitor and Plavix with this. Don't hesitate, just ask and look up your states rules on CBD oil.


They test me for everything here, and never once was my taking pot or drinking EVER brought up. Frankly if I'm honest with my doctors then it's none of anyone's damn business what I do in my home.

[weltschmerz]

May 7, 2018 22:34:08 GMT -5 Jaguar said:

Pat you need to find out for sure if taking this will affect your guardianship with your DD. You need to ask your doctor about taking Lipitor and Plavix with this. Don't hesitate, just ask and look up your states rules on CBD oil.


They test me for everything here, and never once was my taking pot or drinking EVER brought up. Frankly if I'm honest with my doctors then it's none of anyone's damn business what I do in my home.

Me, neither.
Sometimes, they ask if I drink alcohol, and I'll have maybe 4 drinks a year, so that's a no.

[Knee Deep in Water Chloe]

It's legal where I live both medicinally and for ages over 21 for general purchase. 
While I have absolutely no experience with it, I know several people who use chewables, drops, or oils to control or minimize pain. 
But yes, what you're talking about is marijuana. Calling it cannabis doesn't technically change that. Even the states that have legalized it are still struggling to establish how much one person can have/grow/produce, who is allowed in the stores, whether or not the stores are regulated, what to do with kids who have easy access to it, and what to do regarding employees of agencies that receive federal funding, and what to do regarding private companies that don't allow employees to test positive for drug-use. 

Regardless of what you decide, I hope you feel better soon. 

[Bluerobin]

Ask the doctor if you could or should take it.  That is the safest route.  For me, buffered aspirin always worked better than ibuprofen.

[tractor]

Go the Dr route to make sure it doesn’t have a negative interaction with any of your other drugs, the wrong mix can be fatal. My SIL started giving it to her mom and Dad, things started to get worse until they finally went to the Dr who told them it was interacting with one of their prescriptions, and if the dosing was any higher it would be fatal.

Of course it didn’t help that my SIL got it from some questionable sources, and the strength/purity was not accurately reported. If you find out it works, go for it, as with any new drug, just be careful and ask lots of questions (like you’re doing here).

[countrygirl2]

I read further and it said a big problem is since its not tested or approved by the FDA the sources and potency are questionable.  So that is a big issue throughout the system.

And yes, I'm sure Indiana has not refined the law for it yet.  They just approved its use in March of this year. Like I said if I did take it would drop the hydrocodone and arthrotec, the reason I'm worried about these is I have had pancreatitus and worry about effects of meds on it.  Also I know that both are hard on liver, kidneys, etc.  And I'm concerned about my stomach with all this stuff as I have had an ulcer before. I am very uncomfortable taking all this stuff.


Also the pain management doc is trying to steer me to a nerve block in my spine and I don't want them messing with it.  I have as yet met anyone that messing with their spine has helped them so leery of that.  Indiana is so concerned about opiods I think they will eventually cut people off anyway.  I have read nationwide they are making it almost impossible for doctors to prescribe any kind of pain meds.  They are putting their licenses in jeopardy.  Here if you miss an appointment they drop you from the program.  They aren't trying to help people in pain but punish you for being in pain and trying to alleviate it.

[NoNamePerson]

Go for it - what's the worse that can happen?

[Cheesy FL-Vol]

May 8, 2018 7:24:09 GMT -5 NoNamePerson said:

Go for it - what's the worse that can happen?

It could be fatal. See tractor's comment #18.  It is still an unregulated product that varies in potency/mix from manufacturer to manufacturer, I am sure similar to a variety of any other health/vitamin supplements available OTC.

[OldCoyote]

If you are over seventy years old,  if you wake up in the morning,     And there is no pain!

You are dead!!

Wooooo Hooooo, Woke up this morning, Yep, I am alive!

[NomoreDramaQ1015]

CBD does not have THC in it.   THC is what is detected by drug tests and even that is only in your system for a few hours.  At the most it stays 24 hours.   Since most drug testing is off site you know far enough in advance to not partake so you pass.   

The only time I've ever heard about immediate drug testing is when someone at DH's work crashed a forklift and caused injury.   He was drunk.  

Unless you have people knocking on your door at random days and times on a regular basis demanding you immediately pee in a cup you're fine.

Drugs.com is a good resource for looking up interactions.   It was recommended to me by my former boss who is a pharmacist.   I personally find it way more useful than talking to a doctor anymore.  

[countrygirl2]

My husband is just laughing at me because I am so antidrug.

[Cheesy FL-Vol]

May 8, 2018 9:41:03 GMT -5 countrygirl2 said:

My husband is just laughing at me because I am so antidrug.

I am too. Even vitamins make me feel like crap until 3 or 4 hours afterwards so I don't do vitamins. I stopped BC after only a few months because they made me sick. The only thing I take is tylenol when I get a headache that I can tell isn't going to pass unless I do. That is at most a once or twice every few months. I do feel fortunate that (knock on wood) I have no health issues.

I filled pain scrips when I had various surgeries and dental work, but ended up giving the whole bottle to the law enforcement expired drug collection site. Tylenol always did the trick when I had pain in those situations.

[countrygirl2]

I just know most drugs may have something beneficial but the bad effects are so many and in some cases so devastating I wonder about the benefit.  


But as I age and hurt I guess I'm just taking the crap.  I told hubs the other day, look at this 7
pills I'm taking in the morning, hate it.

Premarin, levothyroxine, Lipitor, half a pill, Plavix, diclofenac and misoprostol (components of arthrotec) 

[justme]

May 7, 2018 22:40:23 GMT -5 weltschmerz said:

May 7, 2018 22:34:08 GMT -5 Jaguar said:

Pat you need to find out for sure if taking this will affect your guardianship with your DD. You need to ask your doctor about taking Lipitor and Plavix with this. Don't hesitate, just ask and look up your states rules on CBD oil.


They test me for everything here, and never once was my taking pot or drinking EVER brought up. Frankly if I'm honest with my doctors then it's none of anyone's damn business what I do in my home.

Me, neither.
Sometimes, they ask if I drink alcohol, and I'll have maybe 4 drinks a year, so that's a no.

A lot of pain doctors drug test you. At least in Florida. Supposedly to make sure you're not getting multiple drugs from multiple people (the ones I've been to make you sign a paper saying you'll only get pain drugs from them) or taking things that could interact or I guess high level?

I got my last one to stop drug testing me every visit when I was like dude I come here for migraine botox, you're not even giving me narcotics.

[NoNamePerson]

May 8, 2018 8:26:52 GMT -5 OldCoyote said:

If you are over seventy years old,  if you wake up in the morning,     And there is no pain!

You are dead!!

Wooooo Hooooo, Woke up this morning, Yep, I am alive!

Well crap, someone notify my next of kin that I am dead!!

[countrygirl2]

This seems to be the biggest issue and they can interact with Lipitor and Plavix from what I'm reading, so hum, things to think about. The metabolizing of the drug.  I really don't see much from thyroid or premarin.  Of course if I did take it I would stop the hydrocodone and arthrotec, so that would be a plus.  I can do those on my own, keep the doses low anyway.

Roughly 60 percent of today’s prescribed pharmaceuticals are processed through the liver by the P450 family of enzymes. Unfortunately, cytochrome P450-complex enzymes are also responsible for metabolizing CBD. The double duty required of the P450 enzyme is the basis of all CBD drug interactions.Once CBD enters the liver, it monopolizes all the P450 enzyme processing capability, inhibiting its ability to break down any other hepatically metabolized drugs. The cytochrome P450-complex enzyme becomes entirely preoccupied with processing CBD, with little to no room to break down other compounds also awaiting metabolization.While the P450 enzyme grapples with CBD, the body virtually stops processing any other pharmaceuticals with the same metabolic pathway. Interestingly, it's not the only P450 inhibitor to worry about. Something as benign as a grapefruit comes with a similar warning about possible drug interaction. Although CBD is thought to be a much stronger inhibitor of the P450 enzyme, physicians have long advised their patients to steer clear of grapefruit when taking certain medications.The duration of CBD's effect is pretty unpredictable, at least based on the current body of research. Many external influencers can ultimately lead to a shorter or longer monopolization of the P450 enzymes. The size of the dose apparently plays a role in the duration of influence, but so too does a patient's unique metabolism. It may also come down to the delivery method of the CBD and whether it came from full-spectrum or isolate product. [1]

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