mãn bécômes first in history to be cured of aids

[ty]

San Francisco man becomes first in history to be cured of AIDS

www.rawstory.com/rawreplay/2011/05/san-francisco-man-becomes-first-in-history-to-be-cured-of-aids/

Posted on 05.17.11
By Stephen C. Webster
Categories: Nation


Timothy Ray Brown, a 45-year-old San Francisco man previously known to the medical community as “the Berlin patient,” has become the first person to ever be cured of AIDS.

After a stem cell bone marrow transplant, doctors say his HIV, the infection which causes AIDS, was eradicated.

His bone marrow donor was one of a very small percentage of people who are immune to HIV. He received a second bone marrow transplant after a resurgence of Leukemia, which he’s also since been cured of.

Doctors still aren’t exactly sure what part of his treatment allowed his body to purge the virus, but clinical trials are scheduled to begin in 2012.

This video is from CBS San Francisco, broadcast Monday, May 17, 2011.

[Tennesseer]

Good for the patient. From Wiki about this guy and treatment:

In 2009, Hutter, Eckhard Thiel and others from the Charite Hospital in Berlin, Germany, published a report on the case in the New England Journal of Medicine.[4] Their patient Timothy Ray Brown, a US citizen living in Berlin,[11] had both acute myelogenous leukemia (AML) and HIV. The physicians found a bone marrow donor with a CCR5-¦¤32 mutation in both genomic copies of a gene encoding a cell-surface chemokine receptor called CCR5. Because "almost all strains of HIV" use the CCR5 receptor to enter a host cell, the mutation confers resistance to HIV infection.[3][4] The patient himself was heterozygous for CCR5-¦¤32. Following the transplant procedure, the patient's CD4+ T-cells circulating in the blood were homozygous for CCR5-¦¤32. The macrophages in his bowel, which continued to express wildtype CCR5 (because they hadn't been replaced yet from bone marrow precursors), also had no detectable virus. After 600 days without antiretroviral drug treatment, the patient's blood, bone marrow and bowel HIV levels were below the limit of detection; the virus was thought to be present in other tissues. However, the patient actually had a brain biopsy, in addition to biopsies of his intestines, liver, lymph nodes, bone marrow¡ªbasically, every part of the body that can be biopsied. All were negative for virus. There is no virus in this person's body out to two and a half years off of all anti-HIV drugs. His antibody levels¡ªcalled titers¡ªare declining just the way expected if the patient was vaccinated against HIV and then the levels of antibodies were examined. They'd be very strong in the beginning, but would weaken if they are not re-exposed to the virus. It is believed this patient has no HIV in his body and therefore there is nothing to re-expose him, so the concentration of HIV antibodies in his blood is decreasing. It is predicted that, in a couple of years, his HIV antibody test will be negative.[12]

en.wikipedia.org/wiki/Gero_H%C3%BCtter

[Deleted]

Glad you did this, Kreepy. I was afraid to. This IS good news. I follow AIDS closely because my brother is HIV+. Let's hope Obamacare does not wipe out research, because there is some exciting work going on with AIDS. New studies show 90% of test group that start the cocktail early do not transmit disease, babies born + now testing -, twins with a + and - from the same womb... lots of stuff happening. Since it seems clear gov't is responsible for the HIV/AIDS explosion, possibly for the very first cases, that they should figure out how to kill this monster.
My brother is healthy, no detectable virus any more, but dangerously low T cell count. 10 years and still doing fine. Too bad it mutates so fast they can't make a vaccine.. but they need to keep working.

[Deleted]

People DO show no virus after years of the cocktail, but are not given the cured status. Not sure why this guy was.. Also there are now stories of caution out there about false positive tests that wipe out people's lives, then are found to be negative, and left with no clear status. Lots of gray zone in HIV/AIDS work..

[AgeOfEnlightenmentSCP]

This is very good news indeed.

[ty]

Well Krickitt, I have two gay brothers and 1 gay sister in my family. One brother of mine, heterosexual told them they would die of Aids. He ended up dying from Aids because he slept with a lot of different women. Not only did he die from it, but he infected his wife and unborn child as well. The baby lasted a few months after birth, and the mother died later that year, leaving three other kids without parents. He never went for checkups and since he was heterosexual, he had this idiotic belief that Aids was a gay only disease and he was immune to it.

Sure it's a sad story, but he chose his lifestyle of sleeping around while being married with strange women at the bars o the weekends. I didn't know him all that well. He said I would die from Aids because I had gay friends. He was pretty much ignorant when it came to understanding about gays, heterosexuals and Aids that does not discriminate. It's every ones disease, not just a gay disease.

[Deleted]

Very true. Strongest growth pattern (last I heard) in the US is young, straight people. Sorry about your brother. That sux. He could have lived a long time if he had gotten help with meds.. depending how long ago this was. The meds do cause my brother some problems, though. His wife is -.
They've come so far with pregnancy and HIV now they don't even automatically recommend abortion. Most babies are born -, if Mom is treated while pregnant. Baby steps. I HATE this disease. Seems possible my bro and others will live a natural lifespan. I remember when it was 18 months from diagnoses to death.
I had lots of gay guys as customers in my cab. Disturbing some of the young one's attitude. Like "Whatever, no big deal, if I get it I'll get meds." The old guys living with it and on meds think the young guys are crazy and clueless. Living with HIV is no cakewalk.

[EVT1]

Amazing- and this from a socialist health care system. I wonder how much profit they made off of this guy?

[Deleted]

Amazing- and this from a socialist health care system. I wonder how much profit they made off of this guy?

Actually we don't have a socialist health care system YET. So if you want to give credit, give it to the system that we are changing FROM.

As for a CURE as written in this article. I'm guessing that it was written by someone that is not experience in the medical field. I kind of doubt that a doctor would say that this patient is "cured", same with the leukemia. Leukemia can go into remission & look like it's gone only to come back at a later date. The same "might" be true of AIDS. I would take this article with a grain of salt.

A good friend of mine had Leukemia (2 forms of it at the same time). Doctors felt that he was 1 in a million because he responded so well to drugs. Every now & then it would "come back" (never really gone, just in remission) & more drugs & he was fine. Then on week he was feeling a bit tired & coughing some (like he had a cold) & 9 days later he died. Until they have a treatment that is 99.9% effective, nothing is cured, it's only treated. (my opinion).

[handyman2]

I agree with Old Tex. It has been shown in studies on cancer that your body still has the cells somewhere in the tissue but treatment and sometimes diet change can put them in remission. I had a friend that had lymphatic cancer and after long treatments improved and the doctors were quite direct in telling him that he was not cured but in remission. Ten years later it came back and he in time died from it.
There have been cases in this country where people with aids I know have active aids but they were not cured but in remission according to medical standards. However if aids can be kept in remission that is a major victory.

[Deleted]

My bro has zero detectable virus for years now, because of the meds. He still has the virus, though. Maybe they are calling this guy cured because he is off the meds and no virus load..

You know-- about this "cocktail" of HIV/AIDS meds... when people start them they are told they can never stop. It's a lifetime prescription. I have read about people that threw out the meds and didn't get sick... who knows if they don't stop taking the drugs if people really can go into, and stay, in remission?? BIG money for pharma in HIV meds. Mostly gov't paid, I bet...very expensive... gov't/pharma/AIDS..... the whole HIV/AIDS issue has ALWAYS reeked, IMO. Lots of people feel the same.

[mmhmm]

Oldtex, this development took place in Germany, not the United States. Germany does, indeed, have a national healthcare plan.

Here's an article that goes more into detail as to what was done and the results that have been obtained:

www.aidsmap.com/Stem-cell-transplant-has-cured-HIV-infection-in-Berlin-patient-say-doctors/page/1577949/

[❤ mollymouser ❤]

This seems very promising and encouraging.