dothedd
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Post by dothedd on Apr 19, 2011 10:38:04 GMT -5
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dothedd
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Joined: Dec 27, 2010 20:43:28 GMT -5
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Post by dothedd on Apr 19, 2011 10:47:29 GMT -5
DIA 2011 Features Sessions for Biotechnology Professionals
NEW AND EXCITING DIA 2011
DIA 2011 reflects our vision to be a global forum for innovation to facilitate better health care worldwide. DIA 2011, unlike any other event of its kind, addresses all the tough issues, including manufacturing, multinational clinical trials, ethics, and pricing / reimbursement, facing professionals involved in the discovery, development, and life cycle management of pharmaceuticals, biotechnology, medical devices, and related health care products. It’s a meeting you can’t afford to miss! Go to www.diahome.org/registerDIA2011 for up-to-the-minute information.
TOPICS IN BIOTECHNOLOGY
DIA 2011 is moving in a new direction in an effort to streamline the program and focus on the hottest topics. DIA 2011 features new scope areas for DIA, including coverage of topics related to biotechnology:
Orphan Drug Development: Regulatory Challenges and Initiatives Therapeutic Drug Development for Alzheimer's, Tumors, and Bacterial Infections Roadmap to Efficient Development of Companion Diagnostics The Eyes Have It! The Unique Advantages of Clinical Research in Ophthalmology Trials: PK/PD and Biomarkers in Ophthalmology Drug Shortages in the Treatment of Rare and Orphan Diseases: Challenges, Compromises, and Choices www.diahome.org/DIAHOME/FlagshipMeetings/Overview.aspx?meetingid=23753
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dothedd
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Joined: Dec 27, 2010 20:43:28 GMT -5
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Post by dothedd on Apr 19, 2011 10:50:57 GMT -5
Special Topic: Vaccines DIA 2011 Offers New Learning Experiences: Click on Event Type to display new opportunities: Forum: 90-minute blended presentation and panel discussion Session: 90-minute presentation delivered lecture-style from the podium Symposium: a blend of three 20-minute presentations Workshop: 90-minute interactive/simulation or role-playing opportunity. SIAC Community Showcase: 60 minute topic developed by DIA’s SIAC Community. Tutorial: half day or full day learning experience held on Sunday, June 19; separate registration and fee required.
Attended the Annual Meeting in the past, BUT can’t find your Track? Click here for more information.
*The following list of offerings will feature content in this special topic area. Click on the title for a complete description and confirmed participants. Click here to search the entire DIA 2011 program. 3 Record(s) Event Type Day Time Title Credits Track(s) SESSION Mon, June 20 1:30PM - 3:00PM CBER Therapeutic and Preventive Vaccines Update Track 04 WORKSHOP Mon, June 20 3:30PM - 5:00PM Ethical Issues in Clinical Trials: It's All Shades of Gray Track 01 FORUM Wed, June 22 1:30PM - 3:00PM Scheduling Product Development: Current Industry Practices and New Techniques Track 02 www.diahome.org/DIAHOME/FlagshipMeetings/Topics.aspx?meetingid=23753&topic=Vaccines
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dothedd
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Joined: Dec 27, 2010 20:43:28 GMT -5
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Post by dothedd on Apr 19, 2011 10:56:19 GMT -5
FierceBiotech Researchwww.fiercebiotechresearch.com/?utm_medium=nl&utm_source=internalTaking blood from Fukushima radiation workers in order to prepare for future stem cell transplants in case they are accidently e By ejones Created Apr 18 2011 - 10:21pm Taking blood from Fukushima radiation workers in order to prepare for future stem cell transplants in case they are accidently exposed to high doses of radiation
Contact: Dr Tetsuya Tanimoto tetanimot@yahoo.co.jp 81-902-097-0852 Lancet
In Correspondence published Online First and an upcoming Lancet, Japanese experts suggest that blood products be taken from workers dealing with the ailing Fukushima Nuclear Facility-so that, should they accidently be exposed to high and health-damaging doses of radiation during the clean-up operation, they will be able to receive treatment by undergoing stem cell transplanation using their own cells (autologous transplant). The Correspondence authors are represented by Dr Shuichi Taniguchi, Toranomon Hospital, Tokyo, Japan, and Dr Tetsuya Tanimoto, Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan.
The authors say: "The danger of a future accidental radiation exposure is not passed, since there has been a series of serious aftershocks even [during] this April."
Generally, rapidly dividing cells, such as intestinal-tract cells, reproductive germ cells essential for fertility, and haemopoietic cells, are most vulnerable to radiation, which can depress bone marrow from a dose of about 2 Gy or higher. Haemopoietic cells are the precursor stem cells that later become a wide range of different blood cells in the body.
In previous nuclear disasters and accidents, allogeneic stem-cell transplantation (ie stem cells from a donor) has been used, But this has major limitations, such as time-consuming donor searching, graft failure, graft-versus-host disease (GVHD), or profound immune suppression after transplantation.
Instead of this, the Japanese call for collection of the peripheral blood stem cells (PBSC) of the workers themselves so that they could have future transplants should the need arise. This technique has several advantages over allogeneic transplantation; it does not cause GVHD, and does not require immunosuppressant drugs that make radiation victims even more vulnerable to infection. Further, the technique can more rapidly restore normal haemopoietic functionality in the body, the safety of the collection method is proven, and the cells are easy to freeze and store. Finally, it could be used to treat future leukaemia (a known possibility of radiation exposure) as well as bone marrow defects. But the authors also acknowledge autologous transplant is not perfect since it can rescue injury of bone marrow only and not other tissues, such as gastrointestinal tract, skin, or lung.
The authors say that 107 transplant teams are standing by in Japan to collect and store haemopoietic stem cells from the workers who are striving to restrain the radiation, and more than 50 hospitals in Europe have agreed to help the workers if required. But the Nuclear Safety Commission of Japan is resisting the plan, due to the "physical and psychological burden for nuclear workers", and there being "no consensus among international authoritative bodies, and no sufficient agreement among the Japanese public."
Tanimoto, Taniguchi and colleagues add: "The most important mission is to save the nuclear workers' lives and to protect the local communities. Such an approach would be the industry's best defence: if a fatal accident happened to the nuclear workers, the nuclear power industry of Japan would collapse."
They conclude: "The process to completely shut down the reactors in Fukushima is expected to take years. The risk of accidental radiation exposure will thus accumulate for the nuclear workers and banking of their autologous PBSCs will become increasingly important. A judgment of right or wrong on this scheme must be determined from the standpoint of the nuclear workers and their families, not from a point of view of cost-benefit balance in ordinary times. Toranomon Hospital in Tokyo is ready to harvest and bank autologous PBSCs for the nuclear workers upon request."
### Dr Tetsuya Tanimoto, Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan. T) +81-90-2097-0852 E) tetanimot@yahoo.co.jp
Dr Shuichi Taniguchi, Toranomon Hospital, Tokyo, Japan. T) +81-90-2501-3690 E) taniguchi-s@toranomon.gr.jp
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Source URL: www.fiercebiotech.com/press-releases/taking-blood-fukushima-radiation-workers-order-prepare-future-stem-cell-tra
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dothedd
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Joined: Dec 27, 2010 20:43:28 GMT -5
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Post by dothedd on Apr 30, 2011 11:21:41 GMT -5
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