oped
Senior Member
Joined: Aug 20, 2018 20:49:12 GMT -5
Posts: 4,676
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Post by oped on Dec 21, 2020 13:49:34 GMT -5
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andi9899
Distinguished Associate
Joined: Dec 6, 2011 10:22:29 GMT -5
Posts: 31,600
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Post by andi9899 on Dec 21, 2020 13:54:24 GMT -5
That's fabulous!
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oped
Senior Member
Joined: Aug 20, 2018 20:49:12 GMT -5
Posts: 4,676
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Post by oped on Dec 21, 2020 13:57:12 GMT -5
New Zealand... you think you're better then us... well you are... but fuck you anyway ... lmao...  |
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stillmovingforward
Senior Member
Hanging on by a thread
Joined: Jan 1, 2014 21:52:58 GMT -5
Posts: 3,066
Today's Mood: Don't Mess with Me!
Location: Not Sure Yet
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Post by stillmovingforward on Dec 21, 2020 14:26:15 GMT -5
I can't like this enough!
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skubikky
Senior Member
Joined: Dec 20, 2010 7:37:12 GMT -5
Posts: 3,044
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Post by skubikky on Dec 21, 2020 15:11:09 GMT -5
Yesssssssssssssssssss!!!!!!
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Post by The Walk of the Penguin Mich on Dec 21, 2020 15:12:10 GMT -5
I just showed this to TD. His response....what happens if 2021 is just the second inning? |
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buystoys
Junior Associate
Joined: Mar 30, 2012 4:58:12 GMT -5
Posts: 5,650
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Post by buystoys on Dec 21, 2020 15:13:13 GMT -5
That is great!
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oped
Senior Member
Joined: Aug 20, 2018 20:49:12 GMT -5
Posts: 4,676
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Post by oped on Dec 21, 2020 15:30:16 GMT -5
Well Mich we make a new video. Maybe come up with some new words...
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raeoflyte
Senior Associate
Joined: Feb 3, 2011 15:43:53 GMT -5
Posts: 15,239
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Post by raeoflyte on Dec 21, 2020 16:45:37 GMT -5
Omg...yes...
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irishpad
Well-Known Member
Joined: Aug 14, 2012 20:42:01 GMT -5
Posts: 1,185 
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Post by irishpad on Dec 21, 2020 17:13:36 GMT -5
New Zealand... you think you're better then us... well you are... but fuck you anyway ... lmao... That was my favorite line  |
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TheOtherMe
Distinguished Associate
Joined: Dec 24, 2010 14:40:52 GMT -5
Posts: 28,387
Mini-Profile Name Color: e619e6
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Post by TheOtherMe on Dec 21, 2020 17:22:39 GMT -5
So true and so funny!
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Tennesseer
Member Emeritus
Joined: Dec 20, 2010 21:58:42 GMT -5
Posts: 64,901
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Post by Tennesseer on Dec 21, 2020 18:38:29 GMT -5
New Zealand... you think you're better then us... well you are... but fuck you anyway ... lmao... That was my favorite line I laughed. |
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irishpad
Well-Known Member
Joined: Aug 14, 2012 20:42:01 GMT -5
Posts: 1,185
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Post by irishpad on Dec 21, 2020 18:45:08 GMT -5
My second favorite one was the woman with her computer on Zoom.
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oped
Senior Member
Joined: Aug 20, 2018 20:49:12 GMT -5
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Post by oped on Dec 21, 2020 19:47:38 GMT -5
I liked the older blond lady too.
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oped
Senior Member
Joined: Aug 20, 2018 20:49:12 GMT -5
Posts: 4,676
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Post by oped on Dec 21, 2020 19:50:08 GMT -5
I burst at the toilet paper hoarders every time...
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Deleted
Joined: Nov 26, 2024 23:44:00 GMT -5
Posts: 0
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Post by Deleted on Dec 21, 2020 19:52:10 GMT -5
Best thing I've seen this year!
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justme
Senior Associate
Joined: Feb 10, 2012 13:12:47 GMT -5
Posts: 14,618
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Post by justme on Dec 21, 2020 19:55:25 GMT -5
I really thought this was about a truck, ya know there's a F150 maybe there's a F2020 ?
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oped
Senior Member
Joined: Aug 20, 2018 20:49:12 GMT -5
Posts: 4,676
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Post by oped on Dec 21, 2020 20:07:33 GMT -5
Should I change it? Lol
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Post by empress of self-improvement on Dec 21, 2020 21:32:06 GMT -5
I really thought this was about a truck, ya know there's a F150 maybe there's a F2020 ? I am so glad I wasn't the only one! |
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Lizard Queen
Senior Associate
103/2024
Joined: Jan 17, 2011 22:19:13 GMT -5
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Post by Lizard Queen on Dec 21, 2020 22:10:31 GMT -5
I totally thought that, too. A Ford, of course.
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NancysSummerSip
Community Leader
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Posts: 36,806
Today's Mood: Full of piss and vinegar
Favorite Drink: Anything with ice
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Post by NancysSummerSip on Dec 22, 2020 14:16:24 GMT -5
OMG!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!! Perfect commercial!!!!!!!!!!!!!!!!!!! Funny for a great cause. |
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Gardening Grandma
Senior Associate
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Post by Gardening Grandma on Dec 22, 2020 16:12:24 GMT -5
Great PSA!! I will be so glad to see 2020 gone.
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Works4me
Senior Member
Someone responded to your personal ad - a German Shepherd named Tara wants to have you for dinner...
Joined: May 5, 2012 12:11:37 GMT -5
Posts: 2,576
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Post by Works4me on Dec 22, 2020 23:46:03 GMT -5
I liked the older blond lady too. Current goal in life is to be more like her! |
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Works4me
Senior Member
Someone responded to your personal ad - a German Shepherd named Tara wants to have you for dinner...
Joined: May 5, 2012 12:11:37 GMT -5
Posts: 2,576
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Post by Works4me on Dec 22, 2020 23:50:48 GMT -5
I just showed this to TD. His response....what happens if 2021 is just the second inning? How did you reply? I ask because I've been wondering, "What if the next few years are so dark they make 2020 look like the good old days?" |
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Works4me
Senior Member
Someone responded to your personal ad - a German Shepherd named Tara wants to have you for dinner...
Joined: May 5, 2012 12:11:37 GMT -5
Posts: 2,576
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Post by Works4me on Dec 22, 2020 23:55:27 GMT -5
Thank you so much for posting this. It really is cathartic! |
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laterbloomer
Senior Member
Joined: Dec 26, 2018 0:50:42 GMT -5
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Post by laterbloomer on Dec 23, 2020 8:50:43 GMT -5
I just showed this to TD. His response....what happens if 2021 is just the second inning? I'm starting 2021 in a shut down so I'm thinking it's very possible.  And there is already a new strain of Covid, we'll see if the vaccine works on it. But according to our flu vaccine experience they will probably say we need a new Covid vaccine every year |
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Post by The Walk of the Penguin Mich on Dec 23, 2020 12:20:14 GMT -5
I just showed this to TD. His response....what happens if 2021 is just the second inning? I'm starting 2021 in a shut down so I'm thinking it's very possible. And there is already a new strain of Covid, we'll see if the vaccine works on it. But according to our flu vaccine experience they will probably say we need a new Covid vaccine every year I wish people would quit saying this. The only thing they can say is that they do not know. This is not an influenza virus. All viruses mutate, but you do not need a yearly polio, MMR, or chicken pox vaccine. The vaccine is to the spike protein, which is how the virus gets into the cell. There has been a very small change there, but considering that if too many mutations are done to the spike protein, it will not allow the virus to enter the cells as easily.....which is an evolution disadvantage. As the new mutation is a 2 amino acid change out of the 1190 aa that comprise the spike protein, it is very likely there is no problem for the vaccine. |
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laterbloomer
Senior Member
Joined: Dec 26, 2018 0:50:42 GMT -5
Posts: 4,355
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Post by laterbloomer on Dec 23, 2020 13:25:16 GMT -5
I'm starting 2021 in a shut down so I'm thinking it's very possible. And there is already a new strain of Covid, we'll see if the vaccine works on it. But according to our flu vaccine experience they will probably say we need a new Covid vaccine every year I wish people would quit saying this. The only thing they can say is that they do not know. This is not an influenza virus. |
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justme
Senior Associate
Joined: Feb 10, 2012 13:12:47 GMT -5
Posts: 14,618
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Post by justme on Dec 23, 2020 17:45:04 GMT -5
I'm starting 2021 in a shut down so I'm thinking it's very possible. And there is already a new strain of Covid, we'll see if the vaccine works on it. But according to our flu vaccine experience they will probably say we need a new Covid vaccine every year I wish people would quit saying this. The only thing they can say is that they do not know. This is not an influenza virus. All viruses mutate, but you do not need a yearly polio, MMR, or chicken pox vaccine. The vaccine is to the spike protein, which is how the virus gets into the cell. There has been a very small change there, but considering that if too many mutations are done to the spike protein, it will not allow the virus to enter the cells as easily.....which is an evolution disadvantage. As the new mutation is a 2 amino acid change out of the 1190 aa that comprise the spike protein, it is very likely there is no problem for the vaccine. Do the traditional covid vaccines that aren't yet approved go for the spike protein too or is that just the mrna ones? |
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Post by The Walk of the Penguin Mich on Dec 23, 2020 18:09:51 GMT -5
I wish people would quit saying this. The only thing they can say is that they do not know. This is not an influenza virus. All viruses mutate, but you do not need a yearly polio, MMR, or chicken pox vaccine. The vaccine is to the spike protein, which is how the virus gets into the cell. There has been a very small change there, but considering that if too many mutations are done to the spike protein, it will not allow the virus to enter the cells as easily.....which is an evolution disadvantage. As the new mutation is a 2 amino acid change out of the 1190 aa that comprise the spike protein, it is very likely there is no problem for the vaccine. Do the traditional covid vaccines that aren't yet approved go for the spike protein too or is that just the mrna ones? The AstraZenica vaccine has a different delivery system, but the genetic material is also against the spike protein. This is the protein that they want to block, as it is the way that the virus gets into the cell. If you block this protein, it renders the virus ineffective. I don't know about the rest of the vaccines out there. Natural immunity (acquired via infection) will have a response to the spike protein, plus all of the other proteins on the viral coat. Speculating, this *could* make natural immunity less effective in preventing reinfection as most of the mutations seen are in other proteins on the virus. |
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