Maybe good news

[happyhoix]

Pfizer is started testing a new type of CV 19 vaccine. 

www.nbcnews.com/news/us-news/pfizer-nyu-working-innovative-coronavirus-vaccine-could-be-ready-end-n1200776

It causes a person to develop antibodies without being exposed to the actual virus, and it could be ready by September. 

By September! Wouldn't it be wonderful to see a light at the end of this particularly shitty tunnel?

I understand I'm a science nerd, but really, isn't science fantastic? 

[deminmaine]

I am really hoping, and trying not to get too hopeful, all at the same time?  

[oped]

I’m hesitant. ‘Skipping’ steps on a known and well documented process is one thing. Short tracking a brand new approach?

I’ll have to read more.

[chiver78]

May 6, 2020 6:31:25 GMT -5 oped said:

I’m hesitant. ‘Skipping’ steps on a known and well documented process is one thing. Short tracking a brand new approach?

I’ll have to read more.

☝️ that.

also, there is an actual vaccine already in clinical trials in WA. obviously that needs time to see what the effects are.

[pulmonarymd]

Time frames reported in the news are usually wildly optimistic. If the concept has never ben proven, it needs some sort of study to show it works and doesn't kill people. Cannot put too much faith in an unproven idea.

[busymom]

Although development of a vaccine is necessary, I wouldn't want to be the first to use the vaccine.  Normally there is a long testing phase.  What if the vaccine is not only a dud, but actually does harm, because of the rushed process?  I'll let others be the official guinea pigs, thank you very much...

[billisonboard]

May 6, 2020 11:56:57 GMT -5 busymom said:

Although development of a vaccine is necessary, I wouldn't want to be the first to use the vaccine.  Normally there is a long testing phase.  What if the vaccine is not only a dud, but actually does harm, because of the rushed process?  I'll let others be the official guinea pigs, thank you very much...

I can't come up with any criteria which would put me in even the top 50% of people to receive the vaccine so I am not even worrying about getting it or not before it is well established.

[pulmonarymd]

In my situation, I would volunteer to be part of an effectiveness study. What do I have to lose? Going to be exposed anyway.

[busymom]

May 6, 2020 12:13:30 GMT -5 pulmonarymd said:

In my situation, I would volunteer to be part of an effectiveness study. What do I have to lose? Going to be exposed anyway.

     I agree that someone in the medical field, who has daily exposure to patients, would be a better candidate to try a new vaccine.  And, I do admire the bravery of those willing to be first to try it.

     For someone like me, who no longer is exposed to the public on a daily basis, we can wait.  

[pulmonarymd]

May 6, 2020 13:22:38 GMT -5 busymom said:

May 6, 2020 12:13:30 GMT -5 pulmonarymd said:

In my situation, I would volunteer to be part of an effectiveness study. What do I have to lose? Going to be exposed anyway.

     I agree that someone in the medical field, who has daily exposure to patients, would be a better candidate to try a new vaccine.  And, I do admire the bravery of those willing to be first to try it.

     For someone like me, who no longer is exposed to the public on a daily basis, we can wait.  

I understand and agree with you. Just as I would not try a new treatment for something that already has an effective treatment. I am also not one to be the first to prescribe a new medication if there are alternatives. Life is all a risk/benefit calculation. 

[thyme4change]

If it is "ready by September" - what does that mean? Does it mean it starts getting tested, or is finished getting tested, is ready for FDA approval, or has FDA approval? Does it mean they have the capabilities to start manufacturing it, or that they can start pumping out millions of does?

There are so many milestones between concept and execution, I don't know where human pharmaceuticals put the stage of "ready".

[MN-Investor]

I find all the current research just fascinating. Because of the seriousness of this pandemic, treatments and vaccines are being explored by thousands of scientists around the whole world. One article today talked about looking at the antibodies produced by llamas. Of course many of these avenues will lead to dead ends as far as COVID-19, but they have the potential to steer scientists into a better direction, or notice something that will be effective against some other current or future disease. I LOVE SCIENCE!

(And yes, I'm well aware that I may not get a vaccine for a very long time, but as long as scientists are moving forward with their research, I'm fine with that. Science takes time.)

[happyhoix]

May 6, 2020 13:43:09 GMT -5 thyme4change said:

If it is "ready by September" - what does that mean? Does it mean it starts getting tested, or is finished getting tested, is ready for FDA approval, or has FDA approval? Does it mean they have the capabilities to start manufacturing it, or that they can start pumping out millions of does?

There are so many milestones between concept and execution, I don't know where human pharmaceuticals put the stage of "ready".

From what I saw on TV last night, it is being tested on volunteers right now.  The tests will show whether or not it creates antibodies that allow you to become resistant to CV19 (and that you don't accidentally end up getting CV19 in the process) 

They are expecting these initial trials to have those answers in 4 months - so we'll know if it works or not. If it works, there will be a massive ramp up to creating the vaccine. From what I've read about other vaccines in trials, the pharma companies are planning to share the winning vaccine amongst themselves so they can all mass produce it. So yes it will take some amount of time to generate the vaccine and distribute it. 

Let's hope that gets done fairly, with the elderly and healthcare workers getting it first, and not Trumps golf resort pals. But since initial hopes for an effective vaccine were 12 - 18 months, if we can get it launched in six months, that will be a kind of miracle. Fingers crossed. 

[pulmonarymd]

May 6, 2020 14:31:35 GMT -5 happyhoix said:

May 6, 2020 13:43:09 GMT -5 thyme4change said:

If it is "ready by September" - what does that mean? Does it mean it starts getting tested, or is finished getting tested, is ready for FDA approval, or has FDA approval? Does it mean they have the capabilities to start manufacturing it, or that they can start pumping out millions of does?

There are so many milestones between concept and execution, I don't know where human pharmaceuticals put the stage of "ready".

From what I saw on TV last night, it is being tested on volunteers right now.  The tests will show whether or not it creates antibodies that allow you to become resistant to CV19 (and that you don't accidentally end up getting CV19 in the process) 

They are expecting these initial trials to have those answers in 4 months - so we'll know if it works or not. If it works, there will be a massive ramp up to creating the vaccine. From what I've read about other vaccines in trials, the pharma companies are planning to share the winning vaccine amongst themselves so they can all mass produce it. So yes it will take some amount of time to generate the vaccine and distribute it. 

Let's hope that gets done fairly, with the elderly and healthcare workers getting it first, and not Trumps golf resort pals. But since initial hopes for an effective vaccine were 12 - 18 months, if we can get it launched in six months, that will be a kind of miracle. Fingers crossed. 

If we have an effective vaccine by January, produced in significant numbers to make a difference, will be an incredible accomplishment, and for everything to work perfectly. There are always bumps in the road with these sorts of things

[thyme4change]

May 6, 2020 14:31:35 GMT -5 happyhoix said:

May 6, 2020 13:43:09 GMT -5 thyme4change said:

If it is "ready by September" - what does that mean? Does it mean it starts getting tested, or is finished getting tested, is ready for FDA approval, or has FDA approval? Does it mean they have the capabilities to start manufacturing it, or that they can start pumping out millions of does?

There are so many milestones between concept and execution, I don't know where human pharmaceuticals put the stage of "ready".

From what I saw on TV last night, it is being tested on volunteers right now.  The tests will show whether or not it creates antibodies that allow you to become resistant to CV19 (and that you don't accidentally end up getting CV19 in the process) 

They are expecting these initial trials to have those answers in 4 months - so we'll know if it works or not. If it works, there will be a massive ramp up to creating the vaccine. From what I've read about other vaccines in trials, the pharma companies are planning to share the winning vaccine amongst themselves so they can all mass produce it. So yes it will take some amount of time to generate the vaccine and distribute it. 

Let's hope that gets done fairly, with the elderly and healthcare workers getting it first, and not Trumps golf resort pals. But since initial hopes for an effective vaccine were 12 - 18 months, if we can get it launched in six months, that will be a kind of miracle. Fingers crossed. 

Do they also have prove that the antibodies make you immune? Isn't that still an outstanding question?

[happyhoix]

May 6, 2020 15:28:32 GMT -5 thyme4change said:

May 6, 2020 14:31:35 GMT -5 happyhoix said:

From what I saw on TV last night, it is being tested on volunteers right now.  The tests will show whether or not it creates antibodies that allow you to become resistant to CV19 (and that you don't accidentally end up getting CV19 in the process) 

They are expecting these initial trials to have those answers in 4 months - so we'll know if it works or not. If it works, there will be a massive ramp up to creating the vaccine. From what I've read about other vaccines in trials, the pharma companies are planning to share the winning vaccine amongst themselves so they can all mass produce it. So yes it will take some amount of time to generate the vaccine and distribute it. 

Let's hope that gets done fairly, with the elderly and healthcare workers getting it first, and not Trumps golf resort pals. But since initial hopes for an effective vaccine were 12 - 18 months, if we can get it launched in six months, that will be a kind of miracle. Fingers crossed. 

Do they also have prove that the antibodies make you immune? Isn't that still an outstanding question?

I’ve heard a variety of responses on that, so I don’t know.

[djAdvocate]

May 6, 2020 7:33:06 GMT -5 chiver78 said:

May 6, 2020 6:31:25 GMT -5 oped said:

I’m hesitant. ‘Skipping’ steps on a known and well documented process is one thing. Short tracking a brand new approach?

I’ll have to read more.

☝️ that.

also, there is an actual vaccine already in clinical trials in WA. obviously that needs time to see what the effects are.

there are 108 vaccines on trial at this time.

3 months later, we can decide whether they work.

then, we can approve those that work (if any) for production.

[NastyWoman]

May 6, 2020 11:56:57 GMT -5 busymom said:

Although development of a vaccine is necessary, I wouldn't want to be the first to use the vaccine.  Normally there is a long testing phase.  What if the vaccine is not only a dud, but actually does harm, because of the rushed process?  I'll let others be the official guinea pigs, thank you very much...

I would be hesitant too, but if I were at that stage of my life that I might get pregnant, I would not just be hesitant I would say no effing way!!! Too many times in the past have new "wonder" drugs led to children born with horrible birth defects.

I might be somewhat more willing to take a risk now that I would only put my own life in the balance.

[thyme4change]

May 6, 2020 15:28:32 GMT -5 thyme4change said:

May 6, 2020 14:31:35 GMT -5 happyhoix said:

From what I saw on TV last night, it is being tested on volunteers right now.  The tests will show whether or not it creates antibodies that allow you to become resistant to CV19 (and that you don't accidentally end up getting CV19 in the process) 

They are expecting these initial trials to have those answers in 4 months - so we'll know if it works or not. If it works, there will be a massive ramp up to creating the vaccine. From what I've read about other vaccines in trials, the pharma companies are planning to share the winning vaccine amongst themselves so they can all mass produce it. So yes it will take some amount of time to generate the vaccine and distribute it. 

Let's hope that gets done fairly, with the elderly and healthcare workers getting it first, and not Trumps golf resort pals. But since initial hopes for an effective vaccine were 12 - 18 months, if we can get it launched in six months, that will be a kind of miracle. Fingers crossed. 

Do they also have prove that the antibodies make you immune? Isn't that still an outstanding question?

www.msn.com/en-ca/news/world/scientists-conclude-people-cannot-get-coronavirus-twice/ar-BB13tm64

Someone is feeling good about this answer.

[chiver78]

May 6, 2020 18:21:58 GMT -5 djAdvocate said:

May 6, 2020 7:33:06 GMT -5 chiver78 said:

☝️ that.

also, there is an actual vaccine already in clinical trials in WA. obviously that needs time to see what the effects are.

there are 108 vaccines on trial at this time.

3 months later, we can decide whether they work.

then, we can approve those that work (if any) for production.

108 already on trial? wow. I was unaware of that...  also - there are companies (including my own) working toward antibody therapies with blood donations from people who have recovered. 

as you say though, we need time to see how and if any of these options will work before we unleash them on the public. 

[oped]

Reactivate and reinfect are not necessarily the same thing. But that was positive news. 

[Deleted]

May 7, 2020 7:44:20 GMT -5 oped said:

Reactivate and reinfect are not necessarily the same thing. But that was positive news. 

[Spellbound454]

All though there are lots of vaccines being developed........ only eight have been cleared for human trials..... Some of which have started.

There is no guarantee any will work........ some viruses cant  be vaccinated for........ but there are some very good candidates in the mix.

[djAdvocate]

May 7, 2020 7:17:43 GMT -5 chiver78 said:

May 6, 2020 18:21:58 GMT -5 djAdvocate said:

there are 108 vaccines on trial at this time.

3 months later, we can decide whether they work.

then, we can approve those that work (if any) for production.

108 already on trial? wow. I was unaware of that...  also - there are companies (including my own) working toward antibody therapies with blood donations from people who have recovered. 

as you say though, we need time to see how and if any of these options will work before we unleash them on the public. 

www.cnn.com/world/live-news/coronavirus-pandemic-05-05-20-intl/index.html